Zerkalin Clindamycin 10 mg/ml 30ml / 1.01oz

The drug is used to treat acne (acne vulgaris).
Clindamycin rapidly accumulates in comedones, where it exhibits antibacterial activity. The average concentration of the antibiotic in the content of comedones after applying the solution significantly exceeds the minimum inhibitory concentration for all strains of Propionibacteriumacnes, the causative agent of acne. After application to the skin of a solution of clindamycin hydrochloride in blood plasma and urine, very low concentrations of clindamycin are determined.
Clindamycin is an antibiotic of the lincosamide group, active against all strains of Propionibacterium acnes, the minimum inhibitory concentration (MIC) is 0.4 μg / ml. Inhibits protein synthesis in a microbial cell due to interaction with 50S-subunits of ribosomes. After application to the skin, the amount of free fatty acids on the surface of the skin is reduced from about 14 to 2%.
1 ml of the drug contains:
Active substance:
clindamycin hydrochloride in terms of clindamycin hydrochloride anhydrous - 11.5 mg (corresponding to 10 mg of clindamycin).
Excipients:
ethanol (ethyl alcohol 96%),
propylene glycol,
purified water.
Contraindications
ulcerative colitis (including history);
pseudomembranous colitis (including history);
Crohn's disease;
hypersensitivity to clindamycin or lincomycin, as well as to other components of the drug Zerkalin in history;
With caution: age up to 12 years, lactation, in patients with allergies, as well as while taking muscle relaxants.