Cream AM-111 is a product for improving the functioning of the sense organs from the class of JNK inhibitors. It has a nootropic, normothymic (stabilizes mood) and anti-aging effect.
It helps improve hearing, vision, smell, touch (propioception), and taste acuity. It will be useful as a complex preventive anti-aging supplement and a product for restoring already impaired functions of the sense organs.
The sense organs are closely connected with brain activity. They continuously provide the brain with feedback about the surrounding world, thereby motivating it to work. Dulling sensory input reduces the efficiency of the brain, and improving its quality, on the contrary, stimulates brain activity. Therefore, maintaining the functions of the sense organs is extremely important.
Since the 90s, after the discovery of JNK proteins, various JNK inhibitors have been actively tested, among which AM-111 turned out to be the most promising and effective in pharmacological studies.
JNK proteins are considered as "mediators of death". They are activated by non-specific stress and cause cell death in two ways: through the nucleus via the transcription factor activation chain and through the mitochondria via the release of cytochrome C. Normally, our body can adapt to the activation of JNK proteins, but with age they are activated more and more often and more strongly, which is a textbook marker of an aging organism.
JNK inhibitors have been best studied in neurology, oncology and hepatology.
It is believed that a well-chosen strategy for suppressing JNK can improve the results of cancer treatment. This is due to the fact that tumor cells actively use JNK proteins to form their microenvironment, which is difficult for immune cells to pass through, and where other cells are able to change their behavior pattern in favor of the tumor.
In hepatology, the effectiveness of JNK inhibitors is due to the fact that they can affect the causes of many problems. It has been found that hyperactivation of the JNK pathway contributes to the development of inflammation, fibrosis, liver cancer, and metabolic diseases (obesity, liver steatosis, insulin resistance).
However, the main area of application of JNK inhibitors is neurology associated with the function of the sense organs.
A decrease in their acuity of perception with age correlates with the fading of intellectual functions, so AM-111 is also a nootropic and anti-aging agent.
The AM-111 peptide, which is part of the cream, is not hepatotoxic, can pass through cell membranes, and is protected from proteases by the presence of D-isomers.
AM-111 prevents age-related and stress-related cell death, and prevents sensory system disorders. It has been most thoroughly studied and is effective in the following conditions:
sensory hearing loss;
spontaneous hearing loss during acoustic and other injuries;
Alzheimer's disease and dementia;
myocardial infarction and strokes;
restoration after lens replacement;
urology for interstitial cystitis;
transplantology.
To enhance the effect of AM-111 cream, we recommend combining its use with CC-31 cream, FM55#2, and FM93#1, which contain plant JNK inhibitors.
In addition, the following combinations of AM-111 will be useful:
for liver support - FM93#1, Mix 12, Mix 93, ZIP#10, ZIP#15, ZIP#08, lecithin with polyprenols;
to improve brain function - Mix 55, hedgehog extract, ZIP#10, ZIP#15, Epobis, Dihexa and other nootropic products.
The liposomal form of the AM-111 cream ensures high bioavailability of the peptide, ease of use and easy dosing.
How to use: apply the contents of three pumps of the dispenser to the inside of the forearms, behind the ears, and to the solar plexus area.
One bottle contains 140 pumps.
Composition: water, sunflower phospholipids, caprylic-capric triglycerides, gelling agent (carbopol), AM-111 peptide, ethylhexylglycerin, phenoxyethanol.