The Gut Healer dietary supplement from Dr. Kuzminov contains a combination of two peptides – KPV and larazotide. It is designed to help with inflammatory bowel disease (IBD), leaky gut syndrome, and celiac disease (gluten intolerance).
It effectively stops diarrhea of various origins.
KPV is a three-amino acid peptide (lysine-proline-valine) that has pronounced anti-inflammatory, regenerative, and antimicrobial effects. It has great potential for treating various gastrointestinal diseases, including Crohn's disease and ulcerative colitis.
KPV's anti-inflammatory activity is mediated by inhibiting the synthesis of proinflammatory cytokines (TNF-α, IL-6, IL-1β), which play a key role in gastrointestinal inflammation, and reducing the infiltration of inflammatory cells into the intestinal mucosa. KPV's antimicrobial activity against various pathogens, including bacteria and fungi, helps suppress microorganisms that can exacerbate inflammation and damage to the intestinal mucosa. This reduces inflammatory responses and helps prevent secondary infectious complications.
Due to its regenerative properties, KPV activates tissue regeneration and wound healing, stimulates cell proliferation, and repairs damaged tissue. It improves intestinal epithelial cell regeneration and promotes the healing of ulcers and erosions of the mucosa.
In Crohn's disease and ulcerative colitis, KPV can be used to reduce inflammatory markers and improve the overall health of the intestinal mucosa.
KPV can also help with gastric ulcers and erosions caused by Helicobacter pylori or nonsteroidal anti-inflammatory drugs (NSAIDs).
Larazotide acetate (also known as AT-1001) is a peptide developed for patients with celiac disease, for whom gluten consumption triggers a severe inflammatory response in the intestine.
Larazotide acetate has anti-inflammatory properties and inhibits the activation of gliadin-mediated proinflammatory pathways. It improves the structural integrity of tight junctions between intestinal epithelial cells. It helps restore the integrity of the intestinal barrier, preventing its destruction by gliadin and other harmful factors.
Larazotide acetate also modulates immune cell activity, reducing the production of proinflammatory cytokines and inflammatory mediators.
Larazotide acetate and KPV synergistically enhance each other's effects. Their combined use in the Gut Healer dietary supplement can provide a pronounced synergistic effect in celiac disease, Crohn's disease, and ulcerative colitis:
promotes a more significant reduction in inflammation due to their combined mechanisms of action;
accelerates the restoration and healing of the intestinal mucosa;
strengthens the protection of the intestinal barrier and prevents its destruction.
Directions: Take one capsule twice daily, regardless of meals.
Ingredients: One enteric-coated capsule contains:
psyllium (Plantago psyllium, 499 mg);
KPV peptide 500 mcg;
Larazotide acetate peptide 500 mcg.