Anti-dandruff shampoo Keto plus with Ketoconazole and Zinc pyrithione

1ml contains:
Active ingredients:
Ketoconazole - 20.0 mg
Pyrithione zinc - 10.0 mg (in the form of aqueous dispersion 49% - 21.876 mg)
Excipients: Plain Pearly shampoo base (sodium lauryl sulfate, ethylene glycol monostearate, coconut oil fatty acid monoethanolamides, coconut oil fatty acid diethanolamides, coconut oil fatty acid betaines), propylene glycol, hypromellose, colloidal silicon dioxide, imidourea, magnesium aluminum silicate, concentrated hydrochloric acid, flavoring Swiss bouquet P3043, dye azorubine (carmoisine supra), purified water.
Antifungal agent.
When using shampoo, avoid getting it into your eyes. If shampoo gets into your eyes, rinse them with water.
To prevent withdrawal syndrome during long-term local treatment with glucocorticosteroids (GCS), it is recommended to continue the local use of GCS in combination with Keto Plus shampoo, followed by gradual withdrawal of GCS over 2-3 weeks. In rare cases, increased hair loss has been reported with the use of Keto Plus shampoo.
Drug interactions with Keto Plus have not been described.
Ketoconazole, a synthetic imidazole-dioxalane derivative, has antifungal activity against dermatophytes such as Trichophyton spp., Epidermophyton spp., Microsporum spp and yeast-like fungi such as Candida spp and Malassezia furfur (Pityrosporum ovale).
Zinc pyrithione - has an antiproliferative effect on epithelial cells and exhibits antifungal activity against Pityrosporum ovale and Pityrosporum orbiculare, which cause excessive peeling of the skin.
Keto Plus Shampoo quickly reduces the flaking and itching of the scalp that is commonly associated with dandruff and seborrheic dermatitis.
Absorption of active substances through the skin when applied topically is negligible. Since even with long-term use the content of ketoconazole and zinc pyrithione in the blood is not determined, we can come to the conclusion that the drug does not have a systemic effect.
Treatment and prevention of skin and scalp lesions caused by yeast-like microorganisms Malassezia furfur (Pityrosporum ovale), such as pityriasis versicolor, seborrheic dermatitis of the scalp and various types of dandruff.
Contraindications
Hypersensitivity.
When using Keto Plus shampoo, the development of an overdose is not expected, since the drug is intended for external use only.
In case of accidental ingestion, no special measures are required. To prevent aspiration, do not induce vomiting or use gastric lavage.
Side effects
Keto Plus is generally well tolerated. As with other shampoos, local irritation and itching may occur. Hair may become oily or dry.
Typically, when using Keto Plus shampoo, such phenomena are rarely observed.
In isolated cases, mostly in patients with chemically damaged or gray hair, changes in hair color have been reported.
Since the components of the drug are practically not absorbed when applied topically,
the use of shampoo during pregnancy and lactation is not contraindicated.