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Chlorhexidine is an antiseptic drug for topical use that is active against protozoa gram-positive and gram-negative bacteria, viruses including Treponema pallidum, Chlamidia spp., Ureaplasma spp., Neisseria gonorrhoeae, Trichomonas vaginalis, Gardnerella vaginalis, Bacteroides fragilis, Herpes simplex virus type 2. Some strains of Pseudomonas spp are weakly sensitive to the drug. Proteus spp. and acid-resistant forms of bacteria, spores of bacteria and fungi are also resistant. Chlorhexidine does not interfere with the functional activity of lactobacilli. Retains activity, although somewhat reduced in the presence of blood, pus and other biological fluids.